Which domain of activator proteins recognizes specific DNA sequences?

Study for the University of Toronto BIO230H1 Midterm Exam. Grasp complex concepts with interactive questions and detailed explanations. Prepare effectively to excel in your exam!

The DNA Binding Domain is the part of activator proteins that specifically interacts with particular sequences of DNA. This domain is crucial for the initiation of transcription, as it allows the protein to recognize and bind to specific enhancer or promoter regions of genes. By binding to these DNA sites, the DNA Binding Domain facilitates the recruitment of the transcriptional machinery and other regulatory proteins necessary for gene expression.

In contrast, the other domains mentioned serve different functions. The Transcriptional Domain typically involves interactions that enhance the transcription process but does not specifically recognize DNA sequences. The Activator Domain often refers to regions that enhance the activity of the transcriptional machinery but may not engage with the DNA itself directly. Lastly, the Chromatin Remodeling Domain is involved in altering the structure of chromatin to make DNA more accessible for transcription but does not directly interact with DNA sequences.

Thus, the DNA Binding Domain is exclusively responsible for the specific recognition of DNA sequences, making it the correct answer.

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