What process describes the movement of proteins through nuclear pore complexes?

Study for the University of Toronto BIO230H1 Midterm Exam. Grasp complex concepts with interactive questions and detailed explanations. Prepare effectively to excel in your exam!

The movement of proteins through nuclear pore complexes is best described by gated transport. This process involves specific mechanisms that regulate the passage of molecules in and out of the nucleus. Nuclear pore complexes provide a selective barrier that allows the transport of proteins that possess nuclear localization signals, which are recognized by transport receptors. These receptors facilitate the binding and subsequent translocation of proteins through the nuclear pore.

Gated transport is energy-dependent and allows the nucleus to maintain its distinct environment while selectively allowing the transit of essential proteins and RNA. Unlike direct diffusion, which would not be suited for larger macromolecules like proteins due to size constraints, and vesicular transport, which is a distinct method used for moving larger cargo enclosed in vesicles, gated transport specifically describes the regulated transfer of proteins that utilize the complex architecture of the nuclear pore complex. Facilitated transport, while it refers to the assistance of proteins in crossing membranes, does not accurately depict the nuclear transport mechanism in the context of the nuclear pore's unique role and signaling requirements.

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