What is the primary function of microRNAs?

Study for the University of Toronto BIO230H1 Midterm Exam. Grasp complex concepts with interactive questions and detailed explanations. Prepare effectively to excel in your exam!

MicroRNAs (miRNAs) play a critical role in gene regulation by primarily regulating protein synthesis. They achieve this through their ability to bind to specific messenger RNA (mRNA) molecules, typically resulting in the repression of translation or the degradation of the target mRNA. By doing so, miRNAs control the expression levels of various proteins within a cell, influencing processes such as development, differentiation, and response to environmental stimuli.

The focus on protein synthesis regulation highlights the importance of miRNAs in modulating the expression of genes at the post-transcriptional level. This interaction can either hinder the translation of the mRNA into protein or lead to the mRNA's degradation, thereby preventing the synthesis of that particular protein.

In contrast, promoting mRNA stability involves mechanisms that increase the lifespan of mRNA molecules, which is not a primary function of miRNAs. Similarly, inducing transcription relates to the initiation of gene expression, which is generally governed by other regulatory elements and not directly by miRNAs. Generating energy is a function associated with cellular metabolism and respiration, rather than the regulatory roles of miRNAs in gene expression. Thus, the focus on the regulation of protein synthesis accurately reflects the primary function of microRNAs.

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