What type of protein is a monomeric GTPase?

What type of protein is a monomeric GTPase?

• A. Multi-subunit GTP-binding protein
• B. Single-subunit GTP-binding protein
• C. Membrane-bound protein
• D. Cytoplasmic signaling protein

Answer: (B)

A monomeric GTPase is classified as a single-subunit GTP-binding protein. This type of protein is characterized by its ability to bind and hydrolyze guanosine triphosphate (GTP), which plays a crucial role in various cellular processes, including signal transduction and cell regulation. Monomeric GTPases function as molecular switches, toggling between an active GTP-bound state and an inactive GDP-bound state. The single subunit structure allows them to efficiently regulate signaling pathways without the need for additional subunits, which is typical in multi-subunit proteins. This understanding is important because it highlights the distinct functional roles of monomeric GTPases in contrast to multi-subunit GTP-binding proteins, which can often involve complex formation and multiple interacting components. While monomeric GTPases can be located in different cellular environments, their classification as single-subunit proteins is central to understanding their dynamics and interactions within the cell.

A monomeric GTPase is classified as a single-subunit GTP-binding protein. This type of protein is characterized by its ability to bind and hydrolyze guanosine triphosphate (GTP), which plays a crucial role in various cellular processes, including signal transduction and cell regulation. Monomeric GTPases function as molecular switches, toggling between an active GTP-bound state and an inactive GDP-bound state. The single subunit structure allows them to efficiently regulate signaling pathways without the need for additional subunits, which is typical in multi-subunit proteins.

This understanding is important because it highlights the distinct functional roles of monomeric GTPases in contrast to multi-subunit GTP-binding proteins, which can often involve complex formation and multiple interacting components. While monomeric GTPases can be located in different cellular environments, their classification as single-subunit proteins is central to understanding their dynamics and interactions within the cell.