What is a significant outcome of the positive feedback loop in Drosophila's sex determination?

In Drosophila, the sex determination process involves a complex interplay of genetic factors, and a crucial aspect of this is the positive feedback loop that contributes to the robustness of sex determination. Specifically, the positive feedback loop reinforces the expression of female-specific genes by amplifying the activity of the Sex-lethal (Sxl) gene, leading to the production of the Sxl protein, which is vital for the female sex determination pathway.

The concept of "cell memory" is integral to this process. Once the Sxl protein is sufficiently expressed, it not only promotes further production of itself but also activates other downstream genes necessary for female development. This self-amplification helps the cell "remember" its identity as female even as it continues to divide, leading to a stable and enduring expression pattern that ensures the proper development of female characteristics.

Thus, the strengthening of cell memory is a significant outcome of the positive feedback loop in Drosophila's sex determination, facilitating a stable and reliable system of sex determination throughout the organism's development.