Which process involves the transport of large particles and macromolecules across plasma membranes?

Vesicular transport is the correct process that involves the transport of large particles and macromolecules across plasma membranes. This mechanism encompasses both exocytosis and endocytosis, which are specific types of vesicular transport.

In vesicular transport, cells use membrane-bound vesicles to transport materials into and out of the cell, allowing for the movement of substances that cannot easily cross the membrane due to their size or polarity. Exocytosis refers to the process where substances are expelled from the cell, while endocytosis involves the uptake of materials into the cell. Both processes transform the vesicle membrane into the plasma membrane, enabling the transport of large particles and macromolecules.

The choices surrounding vesicular transport are narrower processes (such as exocytosis and endocytosis) that fit within the broader category. This distinction clarifies that vesicular transport is the overarching mechanism that includes these specific pathways.